Implementation Science

The Global Strategic Information group at IGHS provides responsive and cost-saving assistance to develop, evaluate and bring to scale high-impact and low-cost public health interventions. Our breadth of experience primes us to partner with public health experts in host countries and foster capacity development through incrementally tailoring interventions, developing protocols, designing methods and tools for implementation, data analysis and dissemination of findings.

Our HIV-related activities

Better health outcomes through understanding why HIV patients are not retained in care 

Based on research we have conducted in Kenya and Uganda, we are exploring ways to link innovative sampling-based approaches to understand the effect of loss to follow-up on those patients in HIV care. The premise of the sampling-based approach is to ascertain outcomes in a representative sample of patients who are lost to follow-up. Findings are used to identify “leakages” in the care continuum so that strategies can be identified to better engage patients in care, leading to improved HIV care and treatment programs, and ultimately to improved patient health.

Producing innovative interventions from development to scale

Our research in implementation science is designed to address traditional barriers to delivering evidence-based HIV prevention interventions in real-world, community settings, developing innovative, efficacious interventions and taking them to scale. For example, CLEAR was designed to reduce the sexual and substance use behaviors of youth living with HIV, has been successfully adapted for youth in Uganda. After adapting and implementing this intervention in Uganda, we found that significantly more youth in the intervention used condoms consistently and decreased their number of sexual partners in comparison to the control condition.

Family AIDS Care & Education Services (FACES)

A collaboration between UCSF and Kenya Medical Research Institute (KEMRI), the http://www.faces-kenya.org/Family AIDS Care & Education Services (FACES) is primarily an HIV/AIDS care, treatment and prevention program in the Nyanza region of Kenya and in Nairobi. It supports HIV treatment to more than 140,000 persons in western Kenya and Nairobi at more than 140 mostly Ministry of Health facilities, providing cutting edge treatment based on implementation science findings, particularly around the integration of HIV care into other services, adherence support, tracing, and support for persons with HIV in the community. In addition, FACES provides the platform for a growing number of clinical and implementation research projects. The goal of the program is to enhance local capacity to conduct biomedical and implementation research through training and infrastructure development.