Reducing the global burden of preventable maternal, newborn and child illness and deaths has emerged as a major focus for the global health community. Accelerating progress towards MDGs 4 and 5—the child and maternal health Millennium Development Goals—reached the top of the global political agenda through initiatives such as the UN Global Strategy for Women’s and Children’s Health and the G8 Muskoka Initiative on Maternal, Neonatal, and Child Health (MNCH). An unresolved question in current discussions is how to channel new financial commitments to MNCH in the most rapid, effective, and equitable manner, in order to translate funding into concrete action on the ground. E2Pi conducts evidence synthesis and policy analysis to help address this question. We also examine questions related to the optimum delivery of effective MNCH interventions in low- and middle-income countries.
Why did major global health institutions scale up artemisinin-based combination therapy but ignore combination zinc/oral rehydration therapy?
This Policy Paper uses a scale-up framework to analyze the different trajectories of ACTs and zinc/L-ORS. Such a comparison is valid, given the similarities in the treatment and disease profiles of malaria and diarrhea: (i) both diseases are leading causes of mortality for children under 5 years of age; (ii) care-seeking for both diseases often occurs outside the public sector in low- and middle-income countries; and (iii) for both diseases, public health efforts are aimed at “crowding out” less effective medicines with more effective ones (i.e., replacing older drugs and artemisinin mono-therapy with ACTs, and replacing anti- diarrheal drugs, anti-pyretics, and inappropriate antibiotics with zinc/L-ORS).
In 2011, the the Partnership for Maternal, Newborn & Child Health (PMNCH) contracted SEEK Development in partnership with E2Pi to conduct a major new policy analysis that:
Packages of Care—A Pragmatic Approach to Exploring an Enhanced Role for the Global Fund in Maternal, Newborn and Child Health (MNCH)
At its December 2010 Board meeting, the Global Fund Board discussed whether the Fund should increase its support for MNCH. In an E2Pi Working Paper, which was published ahead of the Board meeting, E2Pi “deconstructed” different packages of MNCH interventions (e.g., antenatal care package, child health package) to explore which specific intervention areas within MNCH the Global Fund might be well placed to support.
What Is the Impact of Integrating HIV with Maternal, Neonatal, and Child Health Services?
In September 2012, UCSF co-hosted a conference, called Integration for Impact, in Nairobi, Kenya, which laid out the latest research on integrating HIV, MNCH, and reproductive health services. To set the scene, an E2Pi Policy Brief summarizes the existing evidence on such integration, laying out research gaps and policy challenges.
A New Scorecard to Track Global Progress on Scaling Up Diarrhea Control Tools
In 2012 and 2013, E2PI conducted in-depth qualitative interviews with 21 child health experts, purposively sampled for their relevant academic or implementation expertise, to explore their views on (a) the value of a scorecard of global diarrhea control and (b) which indicators of successful diarrhea control should be included in such a scorecard. The study was published in PLOS ONE in July 2013.