Improving health and reducing inequities worldwide

Philip Rosenthal, MD

Education & Training

Dr. Rosenthal received his BS in Biochemistry from SUNY at Stony Brook and his medical degree from New York University. He completed his medical residency at the University of Michigan, followed by an Infectious Diseases Fellowship at UCSF. He joined the faculty at UCSF in the Department of Medicine, Division of Infectious Diseases in 1988, and he is now a Professor in the Department.

Dr. Rosenthal was a consultant for the World Health Organization early in his career, working with the Program on AIDS in Malawi. Recently, he has been the Director of the Innovative Translational Collaboration program of the UCSF Clinical and Translational Science Institute (CTSI). He is also a member of the Biomedical Sciences Graduate program. Dr. Rosenthal serves on numerous university committees, has participated on many study sections of the NIH and other research funders, and is currently a member of the World Health Organization Tropical Disease Research Expert Drug Discovery Advisory Committee .

Dr. Rosenthal’s research interests are focused on multiple aspects of malaria, including the biochemistry of malaria parasites, antimalarial drug discovery, and clinical and translational studies of antimalarial drug efficacy and resistance in Africa. Basic science studies center on the characterization of a family of proteases that play a key role in the parasite life cycle. Drug discovery work includes collaborations with a number of chemistry groups to develop new antimalarial drugs, in particular inhibitors of proteases. Translational work in Uganda and Burkina Faso includes randomized trials of new antimalarial therapies, evaluations of malaria in cohorts of children, evaluations of HIV-malaria co-infection, studies of new malaria diagnostic strategies, evaluations of drug pharmacokinetics, and the longitudinal assessment of the impacts of host genetics, parasite genetics, antimalarial immunity, and epidemiological factors on the incidence of malaria.

Dr. Rosenthal was the recipient of a Doris Duke Charitable Foundation Distinguished Clinical Scientist Award. His work has also been funded by the National Institutes of Health, Centers for Disease Control, and Medicines for Malaria Venture. He has published over 180 scientific articles and book chapters on malaria and tropical diseases.